Evaluation of immune response after moderate and overtraining exercise in wistar rat

نویسندگان

  • Abolfazl Khajavi Rad Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mahmoud Hossein Neurocognitive Research Centre, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mohammad Hossein Boskabady Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Mojtaba Sankian Immunology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Zahra Gholamnezhad Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده مقاله:

  Objective(s): The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.   Materials and Methods: Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (OR) (OT plus 2 weeks recovery) groups, (n=6 for each group). Immediately, 24 hr and 2 weeks (in OR) after last bout of exercise blood samples were obtained. The plasma concentrations of TNFα, IL-6, IL-10, IL-4 and IFN were measured by ELISA method. Results: Immediately after last bout of exercise the following findings were observed; IL-6, IL-10 and TNFαconcentrations increased in OT and OR groups compared with control (P

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evaluation of immune response after moderate and overtraining exercise in wistar rat

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عنوان ژورنال

دوره 17  شماره 1

صفحات  1- 8

تاریخ انتشار 2014-01-01

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